If you are looking for one of the best standards in website design layouts, then the new BBC website homepage design will be your first port of call. It was updated two years ago (check out the original 1997 version).
Since then they’ve been busy in the background working on unifying the visual and interaction design of bbc.co.uk and their mobile website. Read the full post explaining their Global Visual Language 2.0. (You can download the full document. 5Mb size).